发明名称 ANTIBODIES AGAINST BACTERIAL PEPTIDOGLYCANS
摘要 Antibodies from the class of the immunoglobulins G against the peptide-subunit pentapeptide L-Ala-D-Glu(L-Lys-D-Ala-D-Ala) of peptidoglycan in biological test material, and against bacterial cell walls containing these peptidoglycans, characterised by a) specific bonding on pentapeptides of the general formula R - A1 - D - Ala (I) in which R represents an amino acid moiety having 1 - 3, preferably 3, amino acids from the group comprising Gly, L-Ala, D-Glu, L-Lys and A1 represents one of the amino acids D-Ala, D-Ser, D-Val or D-Leu, or b) specific bonding on isolated bacterial cell walls containing pentapeptides of the general formula I or c) specific bonding on gram-positive bacteria containing pentapeptides of the general formula I, process for their preparation, methods for their quantitative determination, and their use.
申请公布号 ZA8306125(B) 申请公布日期 1985.04.24
申请号 ZA19830006125 申请日期 1983.08.19
申请人 BOEHRINGER INGELHEIM DIAGNOSTIKA GMBH 发明人 HELMUT KOLB;KARL HEINZ SCHLEIFER;HANS PETER SEIDL;KLAUS DIETER TYMPNER;LUDWIG WEISS
分类号 A61K39/00;G01N33/531;G01N33/564;G01N33/569 主分类号 A61K39/00
代理机构 代理人
主权项
地址