摘要 |
A porous substrate useful for analyzing hydrophilic substances having low molecular weight, for example by liquid chromatography, comprises a cross-linked copolymer having methylol groups, the copolymer being made of styrene or substituted styrene monomer and a cross-linking agent copolymerizable with the monomer, the outer surface thereof being hydrophilic and the inner surface of pores of the substrate being less hydrophilic, and is prepared by subjecting the styrene monomer and the cross-linking agent to suspension polymerisation in water in the presence of a pore regulator and a water-soluble polymer and providing the resultant cross-linked copolymer with methylol groups, e.g. by chloroalkylation followed by hydrolysis. |