摘要 |
Therapeutically useful 1-(substituted-amino)-3-[4-R1O-3-(lower-alkylthio, lower-alkylsulfinyl or lower-alkylsulfonyl)phenoxy]-2-propanols are obtained by reacting a 4-R10-3-(lower-alkylthio, lower-alkylsulfinyl or lower-alkylsulfonyl)phenol with an epihalohydrin and reacting the resulting product with a primary amine. The compounds have both antihypertensive and beta -adrenergic blocking activity and are useful as antihypertensive agents.
|