摘要 |
<p>A pharmaceutically acceptable salt of sulfodehydroabietic acid of the formula:
<CHEM>
for use in the therapeutic treatment or prophylaxis of a gastro-intestinal disease and a salt of sulfodehydro-abietic acid of the formula:
<CHEM>
with lithium, potassium, magnesium, calcium, aluminium, aluminium hydroxide, an alkyl(C1-5)amine, di-alkyl(C1-5) amine, tri-alkyl(C1-5)amine, cycloalkyl(C3-6)amine, di-alkyl (C1-5)amino-alkyl(C1-5)amine, alkoxy(C1-5)-alkyl(C1-5)amine, hydroxy-alkyl(C1-5)amine, alkylene (C2-6)diamine, aralkyl (C7-8)amine, alkyl(C1-5) N-piperidinoacetyl-p-aminobenzoate, alkyl(C1-5) N-prolyl-p-aminobenzoate, alkyl(C1-5) N-pipecolyl-p-amino-benzoate, morpholine, piperazine, 3-(3,4-dihydroxyphenyl)-8,8-dimethyl-1,8-diazoniaspiro[4,5]decane, 1-(2-dimethyl-aminoethyl)-4-phenyl-2-pyrrolidone, homocysteine thiolactone, an alpha -amino acid of the formula:
<CHEM>
wherein R<1> is amino, guanidino, carbamoyl, dimethylthionia, 4-imidazolyl, mercapto or methylthio, R<2> is hydroxy, alkoxy(C1-5), amino, alkyl(C1-8)amino, di-alkyl(C1-5)amino, cycloalkyl(C3-6)amino or p-alkoxy(C1-5) anilino, and A is straight alkylene (C2-5), an omega -amino acid of the formula:
H2N-B-CH2COR<3>
wherein R<3> is hydroxy or alkoxy(C1-5) and B is straight alkylene(C1-5) (the alkylene being optionally substituted with phenyl), or carnosine. </p> |