发明名称 |
13-(1-Oxyl-2,2,6,6-tetramethylpiperylidenyl-4)hydrazone rubomycin hydrochloride with a paramagnetic center and a method of producing same |
摘要 |
A novel chemical compound is 13-(1-oxo-2,2,6,6-tetramethylpiperylidenyl-4)hydrazone rubomycin hydrochloride, featuring a paramagnetic center and corresponding to the formula <IMAGE> The novel compound is formed by reacting rubomycin base with 1-oxo-2,2,6,6-piperidone-4-hydrazone. The novel compound is capable of inhibiting the growth of malignant tumors and is applicable in medicine; it features reduced toxicity, higher antitumor activity and a wider range of action as compared to known rubomycin derivatives.
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申请公布号 |
US4332934(A) |
申请公布日期 |
1982.06.01 |
申请号 |
US19800192964 |
申请日期 |
1980.10.02 |
申请人 |
EMANUEL, NIKOLAI M.;KONOVALOVA, NINA P.;POVAROV, LEONARD S.;SHAPIRO, ANATOLY B.;DYACHKOVSKAYA, RAISA F.;SUSKINA, VALENTINA I.;DENISOVA, LJUDMILA K. |
发明人 |
EMANUEL, NIKOLAI M.;KONOVALOVA, NINA P.;POVAROV, LEONARD S.;SHAPIRO, ANATOLY B.;DYACHKOVSKAYA, RAISA F.;SUSKINA, VALENTINA I.;DENISOVA, LJUDMILA K. |
分类号 |
A61K31/70;A61K31/7028;A61K31/7034;A61K31/704;A61P35/00;A61P35/02;C07H15/252;(IPC1-7):C07H15/24 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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