发明名称 13-(1-Oxyl-2,2,6,6-tetramethylpiperylidenyl-4)hydrazone rubomycin hydrochloride with a paramagnetic center and a method of producing same
摘要 A novel chemical compound is 13-(1-oxo-2,2,6,6-tetramethylpiperylidenyl-4)hydrazone rubomycin hydrochloride, featuring a paramagnetic center and corresponding to the formula <IMAGE> The novel compound is formed by reacting rubomycin base with 1-oxo-2,2,6,6-piperidone-4-hydrazone. The novel compound is capable of inhibiting the growth of malignant tumors and is applicable in medicine; it features reduced toxicity, higher antitumor activity and a wider range of action as compared to known rubomycin derivatives.
申请公布号 US4332934(A) 申请公布日期 1982.06.01
申请号 US19800192964 申请日期 1980.10.02
申请人 EMANUEL, NIKOLAI M.;KONOVALOVA, NINA P.;POVAROV, LEONARD S.;SHAPIRO, ANATOLY B.;DYACHKOVSKAYA, RAISA F.;SUSKINA, VALENTINA I.;DENISOVA, LJUDMILA K. 发明人 EMANUEL, NIKOLAI M.;KONOVALOVA, NINA P.;POVAROV, LEONARD S.;SHAPIRO, ANATOLY B.;DYACHKOVSKAYA, RAISA F.;SUSKINA, VALENTINA I.;DENISOVA, LJUDMILA K.
分类号 A61K31/70;A61K31/7028;A61K31/7034;A61K31/704;A61P35/00;A61P35/02;C07H15/252;(IPC1-7):C07H15/24 主分类号 A61K31/70
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