ALUMINIUM MAGNESIUM CARBONATE

摘要

A new basic aluminium magnesium carbonate of the formula Al2Mg6(OH)14)CO3)2.4H2O is prepared by heating a mixture of aluminium hydroxide and magnesium hydroxide in the proportions of 6 moles of magnesium hydroxide per mole of Al2O3 present in the presence of carbon dioxide in an aqueous medium containing ammonia or a water-soluble organic nitrogen-containing base (e. g. a mono-, di- or tri-alkylamine, or pyridine or piperidine), the amount of ammonia or water-soluble organic base present in the reaction mixture being at least 6 moles per mole of Al2O3 present, at a temperature between 70.degree. and 100.degree.C at atmospheric pressure. The said aluminium magnesium carbonate may be used to give stable pharmaceutical formulations for the treatment of upper gastrointestinal tract disturbances associated with excess acid and pepsin secretion or biliary reflux.