发明名称 Antiprotozoal agents e.g. against Trichomonas vaginalis - contg. racemic-threo-1-para-chloro-phenoxy-1-imidazol-1-yl-3,3-di:methyl- -2-butanol
摘要 <p>New antiprotozoal agents contain racemic-threo-1-(4-chloro- phenoxy) 1-(1-imidazolyl)-3,3-dimethyl-2-butanol (I) and/or its physiologically tolerable acid addition salts. (I) (an antimycotic agent disclosed in DE2850057) has been found to have strong antiprotozoal activity against organisms such as Trichomonas vaginalis, T.foetus, Lamblia intestinalis, Entamoeba histolytica, Histomonas maleagrimitis etc. A combination of antimycotic and antiprotozoal activity is esp. used. (I) is active orally, locally and parenterally. (I) may be administered in the form of pharmaceutical formulations such as tablets, dragees, capsules, pills, granulates, suppositories, solutions, suspensions, emulsions, pastes, ointments, gels, creams, lotions, powders and sprays.</p>
申请公布号 DE3012825(A1) 申请公布日期 1981.10.08
申请号 DE19803012825 申请日期 1980.04.02
申请人 BAYER AG 发明人 HABERKORN,AXEL,DR.;KRAEMER,WOLFGANG,DR.;BUECHEL,KARL-HEINZ,PROF.-DR.
分类号 C07D233/60;C07D521/00;(IPC1-7):61K31/415 主分类号 C07D233/60
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