2-LOWER ALKYL-7-SUBSTITUTED AMINO-2 OR 3-CEPHEM-4- CARBOXYLIC ACID COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF

摘要

New 2-lower alkyl-7-substituted amino-2 or 3-cephem-4-carboxylic acid compounds are provided of the formula: wherein R1 is (C1 to C6)alkyl, R2 is carboxy or a protected carboxy group, R3 is amino or a protected amino group, and A is carbonyl or hydroxy(C1 to C6)alkylene, and the tautomeric forms and pharmaceutically acceptable salts thereof; the new compounds have antimicrobial activity and inhibit the growth of both gram-positive and gram-negative bacteria.