发明名称 Cephalosporins having an oxazolidonyloxamido substituted acyl sidechain
摘要 Cephalosporins of the formula <IMAGE> wherein R is hydrogen, sodium, potassium, or certain ester groups; R1 is in the alpha -configuration and is hydrogen or methoxy; R2 is hydrogen, lower alkyl, cycloalkyl, cycloalkenyl, cycloalkadienyl, substituted or unsubstituted phenyl, benzyl, phenethyl, thienyl, furyl, or pyridyl, or 2-amino-4-thiazolyl; X is -CH2-, -CH2-CH2-, <IMAGE> R3 is hydrogen, <IMAGE> -O-lower alkyl, or certain substituted or unsubstituted heterothio groups; are disclosed. These compounds possess useful antibacterial activity.
申请公布号 US4217348(A) 申请公布日期 1980.08.12
申请号 US19780946479 申请日期 1978.09.28
申请人 SQUIBB, E R & SONS INC 发明人 BREUER, HERMANN;TREUNER, UWE D
分类号 C07D263/26;C07D501/20;(IPC1-7):A61K31/54;C07D501/34;C07D501/36;C07D501/46 主分类号 C07D263/26
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