1-Aryloxy-2-hydroxy-3-[(benzimidazolin-one-substituted alkyl)-amino]-propanes and salts thereof

摘要

Compounds of the formula <IMAGE> wherein R1, R2 and R3 are hydrogen or substituents of various types; R4 is hydrogen, alkyl of 1 to 5 carbon atoms, or optionally substituted aralkyl of 7 to 14 carbon atoms; R5 is a heterocycle; D is alkylene of 1 to 12 carbon atoms; and A is hydrogen or acyl; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as alpha - and beta -adrenergic receptor blocking agents and antidepressants.