| 发明名称 |
Vectors and compounds for direct expression of activated human protein C. |
| 摘要 |
<p>A method for the direct recombinant production of activated protein C is described. DNA compounds, vectors, and transformants useful in the method are also disclosed. The method involves transformation and culture of a host cell with a recombinant DNA vector that encodes a protein C molecules in which the activation peptide is replaced with a cleavage sequence for a cell associated protease.</p> |
| 申请公布号 |
EP0319312(B1) |
申请公布日期 |
1993.11.03 |
| 申请号 |
EP19880311421 |
申请日期 |
1988.12.02 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
BANG, NILS ULRIK;EHRLICH, HARTMUT JOSEF;GRINNELL, BRIAN WILLIAM;JASKUNAS, STANLEY RICHARD, JR. |
| 分类号 |
C12N15/09;C07H21/04;C12N5/10;C12N9/64;C12N15/52;C12N15/57;C12N15/62;C12N15/84;C12P21/02;C12Q1/04;C12R1/91;(IPC1-7):C12N15/57 |
主分类号 |
C12N15/09 |
| 代理机构 |
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