发明名称 IMIDAZOPYRIDINE SUBSTITUTED TROPANE DERIVATIVES WITH CCR5 RECEPTOR ANTAGONIST ACTIVITY FOR THE TREATMENT OF HIV AND INFLAMMATION
摘要 The present invention provides compounds of formula (I) wherein Rand Rare as defined hereinabove. The compounds of the present invention are modulators, especially antagonists, of the activity of chemokine CCR5 receptors. Modulators of the CCR5 receptor may be useful in the treatment of various inflammatory diseases and conditions, and in the treatment of infection by HIV and genetically related retroviruses.
申请公布号 EA009941(B1) 申请公布日期 2008.04.28
申请号 EA20060000480 申请日期 2004.09.28
申请人 PFIZER LIMITED 发明人 STUPPLE PAUL, ANTHONY
分类号 C07D471/04;A61K31/4188;A61K31/4745;A61P31/18;C07D471/02;C07D519/00 主分类号 C07D471/04
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