发明名称 |
NUCLEOPHILE-TRIGGERED DEGRADBLE MATERIALS AND METHODS OF MAKING AND USING THE SAME |
摘要 |
Disclosed herein are degradable materials comprising the reaction product of an oxanorbomadiene crosslinker or derivative thereof and a multivalent nucleophile-terminated compound, wherein the reaction product is a degradable elastic solid capable of entraining cargo. Also disclosed herein are degradable materials comprising a polymeric and hyperbranched crosslinked material made with oxanorbomadiene linkage that can be activated for cleavage at a predetermined rate by addition of a nucleophile. Also disclosed herein are methods of making and using the same. |
申请公布号 |
WO2016090060(A1) |
申请公布日期 |
2016.06.09 |
申请号 |
WO2015US63551 |
申请日期 |
2015.12.02 |
申请人 |
GEORGIA TECH RESEARCH CORPORATION |
发明人 |
FINN, M.G.;HIGGINSON, CODY, JAMES |
分类号 |
A61K47/32;A61K47/18;A61K47/20 |
主分类号 |
A61K47/32 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|