主权项 |
1. Isolated or substantially purified heparan sulphate HS9, wherein following digestion with heparin lyases I, II and III and then subjecting the resulting disaccharide fragments to capillary electrophoresis analysis the heparan sulphate HS9 has a disaccharide composition comprising:DisaccharideNormalised weight percentageΔUA,2S-GlcNS,6S26.0 ± [[2]] 3.0ΔUA,2S-GlcNS10.0 ± [[1]] 2.0ΔUA-GlcNS,6S30.6 ± [[2]] 3.0ΔUA,2S-GlcNAc,6S1.75 ± [[1]] 2.0 or 1.7 ± [[1]] 2.0ΔUA-GlcNS18.0 ± [[2]] 3.0ΔUA,2S-GlcNAc1.2 ± 0.5ΔUA-GlcNAc,6S12.5 ± [[2]] 3.0. |