发明名称 HEPARAN SULPHATE
摘要 A heparan sulphate that binds vitronectin is disclosed.
申请公布号 US2016215072(A1) 申请公布日期 2016.07.28
申请号 US201414893979 申请日期 2014.05.27
申请人 AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 发明人 Cool Simon;Nurcombe Victor
分类号 C08B37/00;A61K31/727;A61L27/50;A61L27/20;A61L27/54 主分类号 C08B37/00
代理机构 代理人
主权项 1. Isolated or substantially purified heparan sulphate HS9, wherein following digestion with heparin lyases I, II and III and then subjecting the resulting disaccharide fragments to capillary electrophoresis analysis the heparan sulphate HS9 has a disaccharide composition comprising:DisaccharideNormalised weight percentageΔUA,2S-GlcNS,6S26.0 ± [[2]] 3.0ΔUA,2S-GlcNS10.0 ± [[1]] 2.0ΔUA-GlcNS,6S30.6 ± [[2]] 3.0ΔUA,2S-GlcNAc,6S1.75 ± [[1]] 2.0 or 1.7 ± [[1]] 2.0ΔUA-GlcNS18.0 ± [[2]] 3.0ΔUA,2S-GlcNAc1.2 ± 0.5ΔUA-GlcNAc,6S12.5 ± [[2]] 3.0.
地址 Singapore SG