| 发明名称 |
Glycosaminoglycan-modified protein, process for the production of this protein, use and pharmaceutical compositions containing the same. |
| 摘要 |
<p>A glycosaminoglycan-modified protein wherein an amino group of a protein is bound to an aldehyde group, which has been formed by reducing and partially oxidizing the reducing terminal sugar moiety of a glycosaminoglycan, which has a high stability in vivo and can retain physiological activity of the protein for a prolonged period of time.</p> |
| 申请公布号 |
EP0454898(A1) |
申请公布日期 |
1991.11.06 |
| 申请号 |
EP19900119607 |
申请日期 |
1990.10.12 |
| 申请人 |
SEIKAGAKU CORPORATION |
发明人 |
SAKURAI, KATSUKIYO;MIYAZAKI, KYOSUKE |
| 分类号 |
C12N9/00;A61K38/00;A61K47/48;C07K1/02;C07K1/107;C07K1/113;C07K5/11;C07K9/00;C07K14/00;C07K14/195;C07K14/37;C07K14/41;C08B37/00;C12N9/96 |
主分类号 |
C12N9/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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