发明名称 |
IMAGING AGENTS AND METHODS. |
摘要 |
<p>The disclosure includes a composition including a poly(L-glutamic acid) and a NIRF dye. It also includes a method including providing to a plurality of cells an imaging agent including poly(L-glutamic acid), a NIRF dye and then imaging the cells to detect the imaging agent. It further includes a dual functional contrast agent including an MRI agent conjugated with an optical imaging agent. A method of detecting cancer is provided including injecting a dual functional contrast agent into a patient and performing both an MRI and an optical scan. The presence of the agent may indicate cancer. A method of detecting cancer by injecting PG-DTPA-Gd-NIR813 into a patient, then detecting the presence or absence of Gd in a cell or tissue of the patient and detecting the presence or absence of NIR813 in a cell or tissue of the patient is provided. The presence of Gd and NIR813 may indicate cancer.</p> |
申请公布号 |
MX2008014337(A) |
申请公布日期 |
2009.06.17 |
申请号 |
MX20080014337 |
申请日期 |
2007.05.11 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM. |
发明人 |
WEI WANG;CHUN LI;MARITES P. MELANCON;JURI GELOVANI;JEFFREY MYERS |
分类号 |
A61K51/00 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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