| 发明名称 |
METHODS AND COMPOSITIONS FOR MODULATING GLUCONEOGENESIS USING PGC-1 |
| 摘要 |
The invention provides novel methods and compositions for modulating gluconeogenesis through modulation of PGC-1 activity or expression. Also provided are methods for identifying compounds that modulate gluconeogenesis through modulation of PGC-1 activity or expression, as well as methods for identifying compounds that modulate the interaction of PGC-1 with PGC-1 target molecules. Further provided are methods for treating disorders characterized by aberrant gluconeogenesis. |
| 申请公布号 |
WO02062297(A2) |
申请公布日期 |
2002.08.15 |
| 申请号 |
WO2002US03240 |
申请日期 |
2002.02.05 |
| 申请人 |
DANA-FARBER CANCER INSTITUTE, INC. |
发明人 |
SPIEGELMAN, BRUCE;YOON, CLIFFORD, HYUNSUK |
| 分类号 |
G01N33/50;A61K38/00;A61K45/00;A61P3/04;A61P3/10;C07K14/47;C12N5/06;C12N5/10;C12N15/09;C12Q1/02;C12Q1/68;G01N27/447;G01N33/15;G01N33/53;G01N33/566 |
主分类号 |
G01N33/50 |
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