发明名称 3-[2-(3-ACYLAMINO-2-OXO-2H-PYRIDIN-1-YL)-ACETYLAMINO]-4-OXO-PENTANOIC ACID DERIVATIVES AND THEIR USE AS CASPASE INHIBITORS
摘要 <p>The present invention provides a compound of formula I: wherein R1, R2, R3, R4, and R5 are as defined herein. The present invention also provides pharmaceutical compositions and methods using such compositions for treating a caspase-mediated diseases and processes for preparing the compounds of the invention.</p>
申请公布号 EP1833794(A1) 申请公布日期 2007.09.19
申请号 EP20050825102 申请日期 2005.11.21
申请人 VERTEX PHARMCEUTICALS INCORPORATED 发明人 CHARRIER, JEAN-DAMIEN;KNEGTEL, RONALD;MORTIMORE, MICHAEL;STUDLEY, JOHN, R.
分类号 C07D213/75;A61K31/4412;A61K31/4436;A61K31/4439;C07D401/06;C07D409/06 主分类号 C07D213/75
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