发明名称 |
METHODS AND REAGENTS FOR IMPROVED SELECTION OF BIOLOGICAL MATERIALS |
摘要 |
Methods, apparatus and compositions for separating a desired or undesired population or subpopulation from a biological sample are disclosed herein. The selection procedure is based on dense particles in a preferred size range from about 50 nanometers to about 2.5 microns. Specific binding agents are bound to the particles that recognize and bind to specific molecules on the targeted population or subpopulation, and the particles are mixed with the sample in such a way as to promote movement of the particles relative to the sample, promoting binding to the targeted population or subpopulation without non-specifically binding to non- targeted populations in the sample. Because of the large particle density, the bound population is separated from the fluid sample by gravity. |
申请公布号 |
CA2790024(C) |
申请公布日期 |
2016.10.18 |
申请号 |
CA20032790024 |
申请日期 |
2003.07.23 |
申请人 |
VERIDEX, LLC |
发明人 |
RUSSELL, THOMAS;MCGANN, PAULINE;MUSICK, MIKE;CIOCCI, MICHAEL |
分类号 |
B01D15/38;C12M1/00;A61L27/00;B03C1/00;B03C1/02;C12M1/26;C12M1/40;C12M1/42;C12N1/00;C12N5/00;C12N5/06;C12N13/00;C12Q1/24;G01N1/34;G01N33/53;G01N33/543 |
主分类号 |
B01D15/38 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|