| 发明名称 |
CARBAPENEMASES FOR USE WITH ANTIBIOTICS FOR THE PROTECTION OF THE INTESTINAL MICROBIOME |
| 摘要 |
This invention relates, in part, to various compositions and methods for protecting the gastrointestinal microbiome from antibiotic disruption. |
| 申请公布号 |
US2016250304(A1) |
申请公布日期 |
2016.09.01 |
| 申请号 |
US201615051187 |
申请日期 |
2016.02.23 |
| 申请人 |
SYNTHETIC BIOLOGICS, INC. |
发明人 |
Kaleko Michael;Connelly Sheila |
| 分类号 |
A61K38/50;C12N9/86;A61K9/00 |
主分类号 |
A61K38/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of protecting a subject's gastrointestinal microbiome, comprising administering an effective amount of a pharmaceutical composition comprising a broad spectrum carbapenemase to a subject in need thereof, wherein:
the subject is undergoing treatment or has recently undergone treatment with a carbapenem antibiotic, and the broad spectrum carbapenemase is capable of degrading or inactivating the carbapenem in the subject's gastrointestinal tract. |
| 地址 |
Rockville MD US |
