| 摘要 |
The present invention discloses salts of a Compound 1:;
useful in the prophylaxis and/or treatment of inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving degradation and/or disruption of cartilage homeostasis, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons. |
| 主权项 |
1. A pharmaceutically acceptable salt of a compound according to Formula (I): wherein the salt is a 1:1:3 Free Base/HCl/H2O adduct and is in a crystalline form, and wherein the 1:1:3 Free Base/HCl/H2O hydrate of the salt is characterized at least by a powder X-ray diffraction peak at any one or more of the following positions: 7.25, 8.31, 8.78, 10.69, 11.96, 12.25, 13.17, 13.74, 16.23, 16.71, 19.26, 19.64, 20.15, 20.57, 20.95, 21.38, 21.69, 22.77, 23.37, 25.14, 25.71, 25.89, 27.66, 28.57, 28.81, 29.17, 29.58, 30.63, 30.94, 32.06, 32.63, 34.14, 36.22, 36.67, and 37.12° 2θ±0.2° 2θ. |
