HETEROCYCLIC COMPOUNDS AND USE THEREOF AS ERK INHIBITORS
摘要
Disclosed are the ERK inhibitors of formula 1.0: [Formula (1.0)] and the pharmaceutically acceptable salts, esters and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
申请公布号
CA2691417(A1)
申请公布日期
2008.12.24
申请号
CA20082691417
申请日期
2008.06.17
申请人
SCHERING CORPORATION
发明人
GAO, XIAOLEI;WANG, TONG;KELLY, JOSEPH M.;SUN, ROBERT;ZHU, HUGH Y.;NAN, YANG;BOGA, SOBHANA BABU;TSUI, HON-CHUNG;PALIWAL, SUNIL;DENG, YONGQI;SHIH, NENG-YANG;COOPER, ALAN B.;DOLL, RONALD J.