发明名称 SUBSTITUTED PYRIDOPYRAZINE AS NOVEL Syk INHIBITOR
摘要 PROBLEM TO BE SOLVED: To provide a spleen tyrosine kinase (Syk) inhibitor for use in the treatment of diseases such as inflammatory diseases, allergic diseases, cell proliferative disease, autoimmune disease or cytopenia.SOLUTION: Provided is a pyridopyrazine compound represented by formula (I), a racemic mixture, enantiomer, diastereomer and tautomer thereof, or a mixture thereof, or a salt thereof, as well as a pharmaceutical composition containing the same, and a method of use therefor. (R1 is hydrogen, halo or the like; R2 is optionally substituted aryl, heteroaryl or the like; and R3 and R4 are hydrogen, optionally substituted lower alkyl or the like.).SELECTED DRAWING: None
申请公布号 JP2016106100(A) 申请公布日期 2016.06.16
申请号 JP20150255844 申请日期 2015.12.28
申请人 HUTCHISON MEDIPHARMA LTD 发明人 SU WEI-GUO;DENG WEI;JI JIANGUO
分类号 C07D471/04;A61K31/4985;A61K31/5377;A61K31/541;A61K31/551;A61K31/553;A61P7/00;A61P7/06;A61P11/06;A61P19/02;A61P25/00;A61P29/00;A61P35/00;A61P35/02;A61P37/02;A61P37/08;A61P43/00;C07D519/00 主分类号 C07D471/04
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