METHOD FOR PREDICTING ISOLATED SEVERE CRANIOCEREBRAL TRAUMA OUTCOME

摘要

FIELD: medicine. SUBSTANCE: method involves making lumbar puncture in lateral position at the level of the third-fourth lumbar vertebrae when the trauma is evaluated as 3-10 scores in Glasgow scale at the first to third day from the moment the patient is admitted in hospital. Plasminogen contents is to be determined in cerebrospinal fluid by applying solid phase immunoenzyme assay ELISA. Mean plasminogen index (MPI) in cerebrospinal fluid is calculated for predicting severe craniocerebral trauma outcome from formula: MPI=(P1<EMI ID=0.1 HE=8 WI=37 TI=CHI>P2)/2 mg/l, where P1 is the plasminogen contents in cerebrospinal fluid at the first day, P2 is the plasminogen contents in cerebrospinal fluid at the third day. The patient MPI value is compared to a reference norm value. The norm value is considered to be plasminogen contents in cerebrospinal fluid equal to 1.65 ± 0.14 mg/l. The MPI value being less than or equal to 1.65 ± 0.14 mg/l, favorable patient survival prognosis is to be given. The MPI value being greater than 1.65 + 0.14 mg/l, unfavorable patient survival prognosis is to be given. EFFECT: reliable survival prediction beginning from the third day. 1 tbl