发明名称 |
Haemophilus influenza outer membrane protein and use thereof in vaccination |
摘要 |
This invention relates to recombinant bacterial outer membrane proteins comprising one or more LB1(f) peptides from surface-exposed loop 3 of MOMP P5 of non-typeable H. influenzae. Polynucleotides encoding these recombinant proteins are also covered. The invention also relates to a method of isolating the recombinant proteins and a vaccine composition for use in the treatment of Haemophilus influenzae infection.
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申请公布号 |
US2003096370(A1) |
申请公布日期 |
2003.05.22 |
申请号 |
US20020203942 |
申请日期 |
2002.10.21 |
申请人 |
BERTHET FRANCOIS-XAVIER JACQUES;DENOEL PHILIPPE;POOLMAN JAN;THONNARD JOELLE |
发明人 |
BERTHET FRANCOIS-XAVIER JACQUES;DENOEL PHILIPPE;POOLMAN JAN;THONNARD JOELLE |
分类号 |
C12N15/09;A61K39/00;A61K39/39;A61P9/00;A61P11/00;A61P27/02;A61P27/16;A61P31/00;A61P37/04;C07K14/195;C07K14/285;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/31;C12P21/02;(IPC1-7):C07K14/195;C07H21/04;C12N15/74;A61K39/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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