发明名称 COMPOUNDS AND METHOD FOR THE TOPICAL TREATMENT OF INFLAMMATION AND PAIN
摘要 Esters of methyl salicylate with certain non-steroidal antiinflammatory drugs (NSAID's) can be used for topical administration to mammals, to elicit a response which combines the antiinflammatory and analgesic effects of the NSAID and the counterirritant effect of the methyl salicylate. Typical NSAID's which can be used in this way are aspirin (acetylsalicilic acid), ibuprofen and indomethacin. Advantageously, the NSAID-methyl salicylate ester is administered in the form of a pharmaceutical composition, such as an ointment, gel, lotion, cream or the like.
申请公布号 WO8702891(A1) 申请公布日期 1987.05.21
申请号 WO1985US02206 申请日期 1985.11.07
申请人 PFIZER INC. 发明人 MCKIE, JAMES, EDWARD;MILNE, GEORGE, MCLEAN
分类号 C07D209/28;(IPC1-7):A61K31/235 主分类号 C07D209/28
代理机构 代理人
主权项
地址