摘要 |
Esters of methyl salicylate with certain non-steroidal antiinflammatory drugs (NSAID's) can be used for topical administration to mammals, to elicit a response which combines the antiinflammatory and analgesic effects of the NSAID and the counterirritant effect of the methyl salicylate. Typical NSAID's which can be used in this way are aspirin (acetylsalicilic acid), ibuprofen and indomethacin. Advantageously, the NSAID-methyl salicylate ester is administered in the form of a pharmaceutical composition, such as an ointment, gel, lotion, cream or the like. |