| 摘要 |
<p>PURPOSE:To obtain the titled high-purity compound which is an intermediate for a dye, etc. in improved yield and through easy purification steps, by hydrogenating a novel nitrobenzene derivative, e.g. a readily preparable 6-methoxy-2-nitrobenzyl cyanide, as a raw material. CONSTITUTION:A novel nitrobenzene derivative, e.g. 6-ethoxy-2-nitrobenzyl cyanide or 6-n-propoxy-2-nitrobenzyl cyanide, expressed by formula I (R is alkyl) as a raw material is hydrogenated, or further the resultant 4-oxo-4,5,6,7-tetrahydroindole is heat-treated or hydrogenated to give a 4-alkoxyindole of formula II, which is then reacted with a hydrogen halide to afford 4-hydroxyindole. The compound of formula I is prepared from m-nitrophenol as a starting material readily.</p> |
