| 发明名称 |
REGULATING ORNITHINE METABOLISM TO MANIPULATE THE HIGH MANNOSE GLYCOFORM CONTENT OF RECOMBINANT PROTEINS. |
| 摘要 |
The present invention relates to a method for manipulating the high mannose glycoform content of recombinant glycoproteins by regulating ornithine metabolism during cell culture. |
| 申请公布号 |
MX2016009084(A) |
申请公布日期 |
2016.10.13 |
| 申请号 |
MX20160009084 |
申请日期 |
2014.12.09 |
| 申请人 |
AMGEN INC. |
发明人 |
Pavel BONDARENKO;Sohye KANG;Chung- Jr HUANG;Hedieh BARKHORDARIAN;Zhongqi ZHANG |
| 分类号 |
C12P21/00;C07K16/00;C12N1/38;C12N5/00 |
主分类号 |
C12P21/00 |
| 代理机构 |
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代理人 |
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