| 发明名称 | Monoclonal antibodies for treatment of cancer | ||
| 摘要 | The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing GT468, including tumor-related diseases such as breast cancer, lung cancer, gastric cancer, ovarian cancer, and hepatocellular cancer. | ||
| 申请公布号 | US9475867(B2) | 申请公布日期 | 2016.10.25 |
| 申请号 | US201514604447 | 申请日期 | 2015.01.23 |
| 申请人 | GANYMED PHARMACEUTICALS AG;Johannes Gutenberg-Universität Mainz | 发明人 | Sahin Ugur;Koslowski Michael;Türeci Özlem |
| 分类号 | A61K39/395;C07K16/18;C07K16/30;A61K47/48 | 主分类号 | A61K39/395 |
| 代理机构 | McAndrews, Held & Malloy, Ltd. | 代理人 | McAndrews, Held & Malloy, Ltd. |
| 主权项 | 1. An isolated antibody having the ability of binding to a peptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NO: 3-10 and 35-79 and mediating inhibition of proliferation of cells expressing a protein comprising the amino acid sequence of SEQ ID NO: 2 and/or are characterized by association of a protein comprising the amino acid sequence of SEQ ID NO: 2 with the cell surface. | ||
| 地址 | Mainz DE | ||