Modular Extracorporeal Systems and Methods for Treating Blood-Borne Diseases

摘要

Extracorporeal systems and methods for treating blood-borne diseases in a subject or for developing drugs to treat blood-borne diseases include various environmental and treatment modules that can be tailored to a specific disease or infection. In certain embodiments of the systems and methods, a blood sample is treated with cold plasma and optionally with hydrostatic pressure, a pulsed electrical field, a pharmaceutical agent, microwave, centrifugation, sonification, radiation, or a combination thereof, under environmental conditions that are effective for the treatment.

主权项

1. An extracorporeal method for treating a blood-borne disease comprising the steps of:
a) removing blood from a subject; b) contacting the blood with an anticoagulant; c) optionally separating the blood into two or more blood fractions; d) optionally modifying the environment of the blood or a blood fraction; e) treating the blood or blood fraction with cold plasma; f) treating the blood or blood fraction with hydrostatic pressure, a pulsed electrical field, a pharmaceutical agent, centrifugation, microwave, radiation, sonification, or a combination thereof; and g) returning at least a portion of the blood or blood fraction to the subject.