主权项 |
1. A compound selected from a heteroarylamine compound represented by Chemical Formula 1, a pharmaceutically acceptable salt thereof, a hydrate thereof and a solvate thereof: wherein, R1 is one to four substituent(s) selected from a halogen atom, C1-C8 alkyl, C1-C8 alkoxy and R2 is a hydrogen atom, C1-C8 alkyl, —(CH2)m—NR3R4 or -A-(CH2)n-(Q)p-R5, A is C6-C15 aryl, 5- or 6-membered heteroaryl containing one to three nitrogen atom(s) or 5- or 6-membered heterocycloalkyl containing one to three heteroatom(s) selected from a nitrogen atom and an oxygen atom, wherein each of the aryl, heteroaryl or heterocycloalkyl may be substituted or unsubstituted with one to three substituent(s) selected from C1-C8 alkyl, C1-C8 alkoxy, C1-C8 haloalkyl and C1-C8 alkoxycarbonyl, L is —NHC(O)— or —C(O)NH—, Z is one to four substituent(s) selected from C1-C8 alkyl, C1-C8 haloalkyl, 5- or 6-membered heteroaryl containing one to three nitrogen atom(s) and 5- or 6-membered heterocycloalkyl containing one to three heteroatom(s) selected from a nitrogen atom and an oxygen atom, wherein the heteroaryl or heterocycloalkyl may be substituted or unsubstituted with C1-C8 alkyl, Q is 5- or 6-membered heterocycloalkyl or biheterocycloalkyl containing one to three heteroatom(s) selected from a nitrogen atom and an oxygen atom, each of R3 and R4 is a hydrogen atom or C1-C8 alkyl, R5 is a hydrogen atom, C(O)OR7 (wherein R7 is a hydrogen atom or C1-C8 alkyl) or C1-C8 alkyl, m is an integer from 1 to 6, n is an integer from 0 to 6, p, which indicates the presence or absence of Q, is 0 or 1, and wherein X1 and X4 are N and X2 and X3 are CH. |