发明名称 |
Dipeptide mimics, libraries combining two dipeptide mimics with a third group, and methods for production thereof |
摘要 |
Monovalent compounds having moieties comprising at least one amino acid side chain are bound to a core molecule, which also comprises a nucleophilic moiety bound to said core molecule. Monovalent compounds also comprise a macrocyclic ring, a nucleophilic moiety, and a spacer group. Monovalent compounds may be combined into bivalent and trivalent compounds, some of which may have a labeling tag. Methods of production of bivalent compounds and contemplated uses thereof are disclosed. |
申请公布号 |
US9562023(B2) |
申请公布日期 |
2017.02.07 |
申请号 |
US201213418917 |
申请日期 |
2012.03.13 |
申请人 |
Burgess Kevin |
发明人 |
Burgess Kevin |
分类号 |
C07D403/14;C07D249/04;C07D241/08;C07D271/10;C07D273/00;C07D401/04;C07D401/12;C07D401/14;C07D403/12;C07D405/14;C07D413/12;C40B40/04;C40B50/08 |
主分类号 |
C07D403/14 |
代理机构 |
Parker Highlander PLLC |
代理人 |
Parker Highlander PLLC |
主权项 |
1. A dipeptide mimic having the structure: wherein R0 is a fluorescein tag, a biotin tag or a polyether tag. |
地址 |
College Station TX US |