COMBINATION OF AN INHIBITOR OF PHOSPHATIDYLINOSITOL 3-KINASE DELTA AND A BCL-2 INHIBITOR, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF

摘要

A combination comprising N-(4-hydroxyphenyl)-3-{6-[((3S)-3-(4-morpholinylmethyl)- 3,4-dihydro-2(1H)-isoquinolinyl)carbonyl]-1, 3-benzodioxol-5-yl}-N-phenyl-5, 6,7,8-tetrahydro-l-indolizine carboxamide, or a pharmaceutically acceptable salt thereof, and idelalisib, or a pharmaceutically acceptable salt thereof, and compositions and uses thereof.