| 发明名称 |
PEGYLATED GROWTH HORMONE ANTAGONISTS |
| 摘要 |
A composition that is a human growth hormone receptor antagonist comprising human growth hormone receptor antagonist G120K, wherein at least one amino acid of human growth hormone receptor antagonist G120K has been mutated to cysteine; and a polytethylene glycol molecule (PEG) conjugated to each cysteine residue in the human growth hormone receptor antagonist G120K mutant. |
| 申请公布号 |
US2017007711(A1) |
申请公布日期 |
2017.01.12 |
| 申请号 |
US201615204425 |
申请日期 |
2016.07.07 |
| 申请人 |
BRODY Richard S. |
发明人 |
BRODY Richard S. |
| 分类号 |
A61K47/48;A61K38/27 |
主分类号 |
A61K47/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1) A human growth hormone receptor antagonist, comprising:
(a) human growth hormone receptor antagonist G120K, wherein at least one amino acid of human growth hormone receptor antagonist G120K has been mutated to cysteine; and (b) a polytethylene glycol molecule conjugated to each cysteine residue in the human growth hormone receptor antagonist G120K mutant. |
| 地址 |
Columbus OH US |
