NEAR-INFRARED SPECTROSCOPY AND DIFFUSE CORRELATION SPECTROSCOPY DEVICE AND METHODS

摘要

There is provided herewith an apparatus, probe, and method for the combination of near-infrared spectroscopy (NIRS) and diffuse correlation spectroscopy (DCS). The apparatus, probe and method allow for the simultaneous detection of NIRS and DCS.

主权项

1. An integrated device comprising:
a first optical waveguide configured to deliver light at a first wavelength towards a tissue; and wherein the first optical waveguide is configured to deliver light at a second wavelength towards the tissue or wherein the device contains a second optical waveguide configured to deliver light at the second wavelength towards the tissue, wherein each of the lights of the first and second wavelengths and any additional wavelengths—configured for absorption spectroscopy are referred to as SO2 light; a third optical waveguide configured to deliver a light at a third wavelength that is different than the wavelengths of the SO2 lights towards the tissue, the light at a third wavelength is referred to as CBF light, and where the third wavelength is either longer or shorter than each of the wavelengths of the SO2 lights; a fourth optical waveguide configured to transmit one or more of the SO2 lights scattered from the tissue; a fifth optical waveguide configured to transmit the CBF light scattered from the tissue; and a probe tip coupled to the distal end of each of the first, second (if present), third, fourth, and fifth optical waveguides (all the waveguides), wherein the distal ends of all these waveguides are aligned linearly at the probe tip; wherein the integrated device is capable of detecting the SO2 and CBF lights simultaneously.