发明名称 APPLICATIONS OF SUBSTITUENT BENZYLOXY GROUP CONTAINING ETHER COMPOUNDS FOR PREPARING ANTITUMOR DRUGS
摘要 Disclosed are applications of substituent benzyloxy group containing ether compounds represented by general formula I for preparing antitumor drugs. The definition of the substituent groups in the formula I are provided in the specification. The compounds having general formula I have desirable antitumor activity, particularly, and have excellent activity against leukemia strain HL-60, lung cancer A549, H157, H460, H520, bladder cancer T24, J82, prostate cancer LNCap, PC-3, rectal cancer HCT8, HCT116, RkO and the like.
申请公布号 EP3040073(A1) 申请公布日期 2016.07.06
申请号 EP20140839919 申请日期 2014.08.22
申请人 SINOCHEM CORPORATION;SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. 发明人 LIU, CHANGLING;GUAN, AIYING;YANG, XIAOPING;CHAI, BAOSHAN
分类号 A61K31/513;A61K31/075;A61K31/15;A61K31/352;A61K31/415;A61K31/4412;A61P35/00;A61P35/02;A61P35/04 主分类号 A61K31/513
代理机构 代理人
主权项
地址