| 发明名称 |
Solid State Forms of Fused Heteroaromatic Pyrrolidinones |
| 摘要 |
Disclosed are chemical entities which are inhibitors of spleen tyrosine kinase (SYK), namely, chemical entities comprising 6-((1R,2S)-2-aminocyclohexylamino)-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[3,4-c]pyridine-3(2H)-one and certain solid state forms thereof. Also disclosed are methods of using the chemical entities to treat disorders such as a cancer. |
| 申请公布号 |
US2016176869(A1) |
申请公布日期 |
2016.06.23 |
| 申请号 |
US201514973180 |
申请日期 |
2015.12.17 |
| 申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED |
发明人 |
Chen Rongliang;ICHIBAKASE Tomonori;MA Chunrong;MATTHEWS Christopher;MOTOYOSHI Hajime;O'BRYAN Colin;YAJI Kentaro;YOSHIKAWA Naoki |
| 分类号 |
C07D471/04;A61K9/20;A61K9/48 |
主分类号 |
C07D471/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound which is 6-((1R,2S)-2-aminocyclohexylamino)-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[3,4-c]pyridine-3 (2H)-one citrate. |
| 地址 |
Osaka JP |
