发明名称 ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
摘要 Described herein are compounds that are estrogen receptor modulators of Formula (I) and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein SERMF is a selective estrogen receptor modulator fragment and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
申请公布号 WO2016097071(A1) 申请公布日期 2016.06.23
申请号 WO2015EP80118 申请日期 2015.12.17
申请人 F. HOFFMANN-LA ROCHE AG;GENENTECH, INC. 发明人 SMITH, NICHOLAS D.;LIANG, JUN;ORTWINE, DANIEL FRED;WANG, XIAOJING;KAHRAMAN, MEHMET;NAGASAWA, JOHNNY Y.;GOODACRE, SIMON CHARLES;RAY, NICHOLAS CHARLES;GOVEK, STEVEN P.
分类号 C07D401/14;A61K31/397;A61K31/4025;C07D205/04;C07D207/08;C07D403/02;C07D403/14;C07D409/02;C07D411/02;C07D413/02;C07D417/02;C07D417/14;C07D493/04 主分类号 C07D401/14
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