发明名称 |
Multiplexed microfluidic approach for nucleic acid enrichment |
摘要 |
A system for enhancing a nucleic acid sample may include a one pump, a denaturing chamber; a microfluidic hydroxyapatite chromatography device configured for performing hydroxyapatite chromatography on the nucleic acid sample, a sample collector, and tubing connecting the pump with the denaturing chamber, the hydroxyapatite chromatography device and the sample collector such that the pump may be used to move the nucleic acid sample from the denaturing chamber to the hydroxyapatite chromatography device and then to the sample collector. |
申请公布号 |
US9322014(B1) |
申请公布日期 |
2016.04.26 |
申请号 |
US201314084937 |
申请日期 |
2013.11.20 |
申请人 |
Sandia Corporation |
发明人 |
VanderNoot Victoria A.;Langevin Stanley Alan;Bent Zachary;Renzi Ronald F.;Ferko Scott M.;Van De Vreugde James L.;Lane Todd;Patel Kamlesh;Branda Steven |
分类号 |
C12Q1/68;G01N30/08;G01N30/66;G01N30/82;C12N15/10;G01N30/60;G01N30/04 |
主分类号 |
C12Q1/68 |
代理机构 |
Dorsey & Whitney, LLP |
代理人 |
Baca Helen S.;Dorsey & Whitney, LLP |
主权项 |
1. A system for enhancing a nucleic acid sample, the system comprising:
at least one pump; at least one denaturing chamber; at least one microfluidic hydroxyapatite chromatography device configured for performing hydroxyapatite chromatography on the nucleic acid sample; at least one sample collector; one or more tubing fluidically connecting the at least one pump with the at least one denaturing chamber, the at least one microfluidic device, and the at least one sample collector such that the pump may be used to move the nucleic acid sample from the at least one denaturing chamber to the at least one microfluidic device and then to the at least one sample collector; and a first enclosure surrounding the at least one pump, the at least one denaturing chamber, and the at least one microfluidic device. |
地址 |
Albuquerque NM US |