发明名称 |
酵素PDE10A阻害剤としてのヘテロ芳香族フェニルイミダゾール誘導体 |
摘要 |
This invention is directed to compounds, which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula 1. The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula 1. |
申请公布号 |
JP5901535(B2) |
申请公布日期 |
2016.04.13 |
申请号 |
JP20120543475 |
申请日期 |
2010.12.15 |
申请人 |
ハー・ルンドベック・アクチエゼルスカベット |
发明人 |
プーシュル,アスク;ニールセン,ヤコブ;ケフラー,ヤン;キルバーン,ジョン,ポール;マリゴ,マウロ;ランガード,モルテン |
分类号 |
C07D471/04;A61K31/437;A61K31/4985;A61K31/519;A61P25/14;A61P25/16;A61P25/28;A61P25/30;A61P25/32;C07D487/04 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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