<i>Staphylococcus aureus </i>proteins and nucleic acids

摘要

The invention provides proteins from Staphylococcus aureus including amino acid sequences and the corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies and also as targets for antibiotics.

主权项

1. A composition comprising (1) an immunologically effective amount of an isolated polypeptide comprising (a) an amino acid sequence which has at least 95% sequence identity to SEQ ID NO: 700, or (b) a fragment of SEQ ID NO: 700, wherein the fragment of SEQ ID NO: 700 includes at least ten consecutive amino acids from SEQ ID NO: 700, and (2) a pharmaceutically acceptable excipient, wherein concentration of the isolated polypeptide is at least 1 μg/ml.