发明名称 |
RUTHENIUM COMPLEXES AND THEIR USES AS CATALYSTS IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND RELATED REACTIONS |
摘要 |
The present invention relates to novel Ruthenium complexes of formulae A1-A4 and their use, inter alia, for (1) dehydrogenative coupling of alcohols to esters; (2) hydrogenation of esters to alcohols (including hydrogenation of cyclic esters (lactones) or cyclic di-esters (di-lactones), or polyesters); (3) preparing amides from alcohols and amines -(including the preparation of polyamides (e.g., polypeptides) by reacting dialcohols and diamines and/or polymerization of amino alcohols and/or forming cyclic dipeptides from p-aminoalcohols; (4) hydrogenation of amides (including cyclic dipeptides, polypeptides and polyamides) to alcohols andamines; (5) hydrogenation of organic carbonates (including polycarbonates) to alcohols or hydrogenation of carbamates (including polycarbamates) or urea derivatives to alcohols and amines; (6) dehydrogenation of secondary alcohols to ketones; (7) amidation of esters (i.e., synthesis of amides from esters and amines); (8) acylation of alcohols using esters; (9) coupling of alcohols with water and a base to form carboxylic acids; and (10) preparation of amino acids or their salts by coupling of amino alcohols with water and a base. The present, invention further relates to the use of certain known Ruthenium complexes for the preparation of amino acids or their salts from amino alcohols. |
申请公布号 |
WO2016035080(A1) |
申请公布日期 |
2016.03.10 |
申请号 |
WO2015IL50887 |
申请日期 |
2015.09.03 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD. |
发明人 |
MILSTEIN, DAVID;HU, PENG;FOGLER, ERAN;RAO, JAI ANAND GARG NARAYANA |
分类号 |
B01J31/28;C07C29/149;C07C67/00;C07C209/00;C07C209/50;C07C213/00;C07C227/02;C07C231/02;C07C231/08;C07C231/10;C07F15/00 |
主分类号 |
B01J31/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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