| 发明名称 |
ANTI-VEGFR2 ANTIBODY THERAPY FOR HEPATOCELLULAR CARCINOMA |
| 摘要 |
The invention provides for a human antibody that binds to human vascular endothelial growth factor receptor 2, preferably ramucirumab, for the treatment of hepatocellular carcinoma in patients having levels of alpha-fetoprotein (AFP) of 1.5 ULN or greater, and as a predictive method for the treatment of HCC in patients having AFP levels of 1.5 x ULN or greater. |
| 申请公布号 |
WO2016025464(A1) |
申请公布日期 |
2016.02.18 |
| 申请号 |
WO2015US44632 |
申请日期 |
2015.08.11 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
ABADA, PAOLO BENJAMIN;CHANG, SHAO-CHUN;HSU, YANZHI;YANG, LING |
| 分类号 |
A61K39/395;A61P35/00;C07K16/28;C07K16/30;G01N33/574 |
主分类号 |
A61K39/395 |
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