发明名称 SOLUBLE GUANYLATE CYCLASE ACTIVATORS
摘要 <p>A compound of Formula (I): or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate (cGMP) and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of Formula I, or a pharmaceutically acceptable salt thereof, for their use in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of Formula (I) or a pharmaceutically acceptable salt thereof.</p>
申请公布号 EP2575473(B1) 申请公布日期 2016.01.20
申请号 EP20110787236 申请日期 2011.05.24
申请人 MERCK SHARP & DOHME CORP. 发明人 RAGHAVAN, SUBHAREKHA;STELMACH, JOHN, E.;SMITH, CAMERON, J.;LI, HONG;WHITEHEAD, ALAN;WADDELL, SHERMAN, T.;CHEN, YI-HENG;MIAO, SHOUWU;ORNOSKI, OLGA, A.;GARFUNKLE, JOIE;LIAO, XIBIN;CHANG, JIANG;HAN, XIAOQING;GUO, JIAN;GROEPER, JONATHAN, A.;BROCKUNIER, LINDA, L.;ROSAUER, KEITH;PARMEE, EMMA, R.
分类号 A01N43/90;A61K31/519 主分类号 A01N43/90
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