发明名称 |
TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF |
摘要 |
Nanoparticles and microparticles, and pharmaceutical formulations thereof, containing conjugates of an active agent such as a therapeutic, prophylactic, or diagnostic agent attached to a targeting moiety, such as a somatostatin receptor binding moiety, via a linker have been designed. Such nanoparticles and microparticles can provide improved temporospatial delivery of the active agent and/or improved biodistribution. Methods of making the conjugates, the particles, and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided, for example, to treat or prevent cancer or infectious diseases. |
申请公布号 |
CA2953371(A1) |
申请公布日期 |
2016.01.07 |
申请号 |
CA20152953371 |
申请日期 |
2015.06.30 |
申请人 |
TARVEDA THERAPEUTICS, INC. |
发明人 |
ALARGOVA, ROSSITZA G.;BILODEAU, MARK T.;DUNBAR, CRAIG A.;KADIYALA, SUDHAKAR;SHINDE, RAJESH R.;LIM SOO, PATRICK;SWERYDA-KRAWIEC, BEATA;WHITE, BRIAN H.;BAZINET, PATRICK ROSAIRE;WOOSTER, RICHARD |
分类号 |
A61K51/00;A61K9/14 |
主分类号 |
A61K51/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|