| 发明名称 |
MOBILIZATION OF HEMATOPOIETIC STEM CELLS FROM BONE MARROW TO BLOOD USING A COMBINATION OF A ROBO4 RECEPTOR ANTAGONIST AND A CXCR4 ANTAGONIST OR hrVEGF-165 AND A CXCR4 ANTAGONIST |
| 摘要 |
The invention herein disclosed provides for compositions, methods for synthesizing said compositions, and methods for using said compositions, wherein the compositions and methods may be used in clinical treatment using hematopoietic transplantation, particularly to those relating to treatment of cancer and metastasis. The compositions regulate mobilization of hematopoietic stem cells (HSCs) between bone marrow (BM) and the peripheral blood (PB). |
| 申请公布号 |
US2015366943(A1) |
申请公布日期 |
2015.12.24 |
| 申请号 |
US201313261991 |
申请日期 |
2013.05.17 |
| 申请人 |
The Regents of the University of California |
发明人 |
Forsberg E. Camilla;Smith-Berdan Dr. Stephanie |
| 分类号 |
A61K38/19;A61K38/18;A61K38/17 |
主分类号 |
A61K38/19 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition, the composition comprising a Robo4 receptor antagonist and a Cxcr4 antagonist. |
| 地址 |
Oakland CA |
