METHODS FOR IMMOBILIZING CELLS

摘要

The present invention relates to a method for immobilizing a cell on a solid substrate, comprising the steps of: (a) coating on the solid substrate a peptide which comprises a Arg-Gly-Asp sequence and a cysteine residue at its terminal; and (b) contacting the cell to the peptide coated on the solid substrate. The present invention also relates to a novel peptide for cell immobilization, a microarray and a biosensor. According to the present invention, cells particularly animal cells are effectively immobilized on the solid substrate without cytotoxicity in a more specific manner. Interestingly, the present invention permits cells to be immobilized on nano-patterns utilized in cell chips with cellular microenvironments.