The present invention relates to compounds that inhibit bacterial gyrase and/or Topo IV and pharmaceutically acceptable compositions comprising said compounds. These compounds, and compositions thereof, are useful in treating bacterial infection. Accordingly, the present invention also relates to methods for treating bacterial infections in mammals.
申请公布号
ZA200701629(B)
申请公布日期
2008.09.25
申请号
ZA20070001629
申请日期
2004.10.21
申请人
VERTEX PHARMACEUTICALS INCORPORATED
发明人
CHARIFSON, PAUL S.;DEININGER, DAVID D.;GRILLOT, ANNE-LAURE;RONKIN, STEVEN M.;STAMOS, DEAN;PEROLA, EMANUELE;WANG, TIANSHENG;LE TIRAN, ARNAUD;DRUMM, JOSEPH;LIAO, YUSHENG