| 发明名称 |
RNA ANTAGONIST COMPOUNDS FOR THE INHIBITION OF APO-B100 EXPRESSION |
| 摘要 |
Short oligonucleotides directed against the Apo-B100 gene are provided fo r modulating the expression of Apo-B100. Methods of using these compounds fo r modulation of Apo-B100 expression and for the treatment of diseases associ ated with Apo-B100 expression are provided. The oligonucleotides comprise de oxyribonucleosides and locked nucleic acids.
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| 申请公布号 |
CA2681406(A1) |
申请公布日期 |
2008.09.25 |
| 申请号 |
CA20082681406 |
申请日期 |
2008.03.19 |
| 申请人 |
SANTARIS PHARMA A/S |
发明人 |
HANSEN, HENRIK FRYDENLUND;HANSEN, BO;ROSENBOHM, CHRISTOPH;STRAARUP, ELLEN MARIE |
| 分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
| 代理机构 |
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