发明名称 |
METHODS FOR CONVERSION OF TYROSINE TO P-HYDROXYSTYRENE AND P-HYDROXYCINNAMIC ACID |
摘要 |
<p>Three different reaction steps were combined to provide methods for preparing p-hydroxystyrene and p-hydroxycinnamic acid monomers from tyrosine. The three steps include reductive alkylation of tyrosine, followed by oxidation to the N-oxide, and thermal Cope elimination. During Cope elimination, either p-hydroxycinnamic acid or p-hydroxystyrene was produced depending on the absence or presence of base, respectively. Additionally, p-acetoxystyrene may be prepared by reacting the prepared p-hydroxystyrene either directly or after isolation with an acetylating agent.</p> |
申请公布号 |
WO2008085512(A1) |
申请公布日期 |
2008.07.17 |
申请号 |
WO2007US26515 |
申请日期 |
2007.12.28 |
申请人 |
E.I. DU PONT DE NEMOURS AND COMPANY;SHUEY, STEVEN, W.;SHAH, MUKESH, C. |
发明人 |
SHUEY, STEVEN, W.;SHAH, MUKESH, C. |
分类号 |
C07C51/377;C07C37/00;C07C65/19;C07C67/08;C07C69/16 |
主分类号 |
C07C51/377 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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